A clinical study of 1215 Danes aged 18 to 28 years had 28% fewer sperm cells among participants who used cannabis at least once a week compared to those who did not. But, the mechanism behind this correlation is not identified.

What is the relationship between the endocannabinoid system and the male reproductive system?

A study published in September 2019 investigated the complex relationship between the endocannabinoid system (ECS) and the male reproductive system to ultimately determine the potential impact of cannabis use on a man’s fertility.

Scientists discover that the endocannabinoid system and the male reproductive system were closely linkable. Also,the researchers used immunohistochemistry. To selectively reveal different components of the endocannabinoid system in at different stages of sperm formation.

What are the consequences for cannabis users?

The effects of cannabis on fertility are still poorly explainable . The most important conclusion of this study is that the endocannabinoid system and the male reproductive system are closely connectable. The endocannabinoid system appears to regulate sperm production and is particularly active in later stages of spermatogenesis when mature sperm are formed.

Maybe,future research may uncover a mechanism by which cannabis affects the sperm production process, the quality of a man’s sperm and the male reproductive system in general. For the time being, the link between endocannabinoid and the male reproductive system may be sufficient to convince some cannabis users to refrain when trying to conceive a child, especially when they encounter difficulties on one side or the other.

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