Neurofibromatosis type 1 (NF1) is a common genetic disease. Pain is a major symptom of this disease that may be secondary to the development of plexiform and subcutaneous neurofibromas, musculoskeletal symptoms (such as scoliosis and pseudoarthrosis) and headaches.
Visible neurofibromas add significant psychosocial distress to patients. Along with chronic pain, psychosocial distress contributes to associated mood disorders such as depression and anxiety.
A human case study was conducted by physicians in Toronto, Canada. You can view it by clicking on this link.
Cannabis has been studied extensively for the treatment of several conditions. Including epilepsy, multiple sclerosis, Parkinson’s disease, and many chronic pain conditions.
A 25-year-old woman with neurofibromatosis was studied by doctors for symptoms of chronic pain, depression, and anxiety. They administered a dose of medical cannabis consisting of 20 mg CBD and 1 mg THC, slowly increasing the daily morning and evening doses.
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CBD has shown anti-inflammatory and analgesic properties on neurofibromatosis, as well as a mood-stabilizing and anxiolytic effects.
The person concerned claimed that his pain sensations had decreased from 6 to 1 on a scale of 10. Less emotional and more serene and calm, his anxiety seems to have gradually decreased while maintaining a normal mood.
Thanks to this intake, the patient was able to reduce her intake of pain medication.