Dental plaque is a global health problem that affects people of different age groups. Several products exist, but almost all of those that effectively derived from chemicals. A study shows the action of two cannabinoids, CBD and CBG, on the plaque.
Study of the action of CBD and CBG compared to conventional mouthwashes
Cannabinoids are attracting enormous research attention because of their beneficial properties for various applications. A preliminary observation on the antimicrobial property of cannabinoids against plaque bacteria has recently published. It is available by clicking on this link. It discusses the in vitro evaluation of cannabinoid-infused mouthwash products concerning the total cultivable (aerobic) bacterial content of dental plaque samples.
The course of the study
In vitro against fully cultivable bacteria from dental plaque samples taken from 72 adults aged 18 to 83 years. Scientists tested two cannabinoid-infused mouthwash products containing cannabidiol (CBD) and cannabigerol (CBG)
In order to compare the efficacy of cannabinoid products, they included two of the most commonly available over-the-counter products to represent commercially available mouthwash products and the 0.2% chlorhexidine digluconate gold standard as a positive control.
Product A represents a mouthwash containing essential oils and alcohol, and Product B an alcohol-free mouthwash containing fluorine.
Improved efficacy of cannabinoid products
On average, cannabinoid-infused mouthwash products have shown bactericidal efficacy similar to that of 0.2% chlorhexidine.
The various points of note :
- Chlorhexidine 0.2% and cannabinoid mouthwashes were effective against all samples tested.
- Product A showed no significant antimicrobial activity in any of the samples tested.
- Product B showed no detectable inhibition zones in any of the test samples.
- Although the difference in performance was slightly higher than that of chlorhexidine in both cases, the difference was statistically significant for CBD mouthwash and almost significant for CBG mouthwash.
- No significant difference observed between CBD and CBG mouthwashes.
Our in vitro results demonstrate the potential of cannabinoids in the development of effective and safer mouthwash products and new generation fluorine- and alcohol-free oral care products. We believe that this is the first report on such an effective mouthwash with natural ingredients, including cannabinoids and without any fluoride or alcohol.