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CBD (Cannabidiol) is now recognized for its use of inflammation. This time, it is the University of the Sorbonne in Paris that is demonstrating how this cannabinoid can reduce inflammation in brain cells. Sorbonne University: How CBD reduces inflammation in brain cells

In fact a study has recently been published, freshly carried out by a team of French scientists, at the Sorbonne University, Brain and Spinal Cord Institute (ICM), in Paris, France. You can, of course, consult it, by clicking on this link.

Microglia are a population of cells that form the main active immune defense of the central nervous system.

Research on microglia cells has also shown that CBD has anti-inflammatory effects against microglia, including antioxidant effects:

So the effects of CBD were mainly receptor-independent and only slightly attenuated by blocking CB2 receptors. We also established that CBD inhibits a mechanism involving, sequentially, NADPH oxidase-mediated ROS production and NF-κB-dependent signaling events.

The authors wrote that these results “further confirm that CBD may have therapeutic utility in cases where neuro-inflammatory processes are important”.

Finally, these various observations suggest that CBD exerts its anti-inflammatory effects on microglia through an intrinsic antioxidant effect, which is amplified by the inhibition of glucose-dependent NADPH synthesis. These results also confirm that CBD may have therapeutic utility in conditions where neuroinflammatory processes are important.

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