Cannabidiol, one of the compounds in cannabis, is believed to reduce the frequency and severity of seizures in people with severe epilepsy.
Researchers at the University of Alabama (USA) have discovered that cannabidiol (CBD), one of the active compounds in cannabis, could treat adults and children with a severe form of epilepsy that is difficult to treat.
The scientists conducted a study of 120 children with Dravet syndrome, severe epilepsy of genetic origin. These children took either a cannabidiol oil extract or a placebo for 14 weeks. At the end of the test, patients in the “cannabis group” experienced a 39% reduction of their epileptic seizures on average compared to an average decrease of 13% in the placebo group.
A reduction in seizure frequency and severity
Another study involved a group of 171 adults with Lennox-Gastaut syndrome. To be part of the test group, patients had to experience at least two seizures per week.
Again, half of the patients took CBD, and half took a placebo for 14 weeks. At the end of this trial, patients in the “cannabis group” experienced an average reduction of 44% of their seizures compared reduction of 22% in the placebo group.
Our research confirms that CBD can reduce seizure frequency, but we also found that it appears to reduce seizure severity, which is a new finding, says Dr. Jerzy Szaflarski, professor of neurology and lead author of the study.